During early fetal development. the primitive urogenital system is bipotential and can develop into a male or female direction, depending on the chromosomal sex of the fetus. In this chapter, regulatory factors of sex determination and differentiation are described. The roles of two testicular hormones, testosterone and anti-Mullerian hormone (AMH), which are essential for proper differentiation of the internal genitalia, are discussed.

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J.A. Grootegoed (Anton)
Erasmus University Rotterdam
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO)
hdl.handle.net/1765/17657
Erasmus MC: University Medical Center Rotterdam

Visser, J.A. (1998, September 23). Anti-Mullerian Hormone: Molecular Mechanism of Action. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/17657