The shortage of deceased donor kidneys for transplantation has resulted in the expansion of living donation programs. A number of possibilities have been explored, since it became clear that donors do not need to be genetically related to their recipients. Apart from classical direct donation, other options such as paired exchange, list exchange, altruistic donation and domino paired exchange programs have been implemented. In the Netherlands, patients who cannot be transplanted with their potential living donor because of ABO blood group incompatibility or a positive crossmatch, have the option to participate in a national paired kidney exchange program. The practical issues related to this program are described. The 5-years experience with the Dutch kidney exchange program is very positive as, so far, 42% of the recipients included have been transplanted. Recommendations are given for a successful implementation of a common kidney exchange program of different transplantation centers focusing on the advantage of a central histocompatibility laboratory.

Netherlands, article, government regulation, health care planning, health care policy, health care quality, histocompatibility test, human, kidney transplantation, laboratory, legal aspect, living donor, organization, organization and management, program development, public health, transplantation
hdl.handle.net/1765/17705
Clinical Transplants
Erasmus MC: University Medical Center Rotterdam

de Klerk, M, Witvliet, M.D, Haase-Kromwijk, B.J.J.M, Weimar, W, & Claas, F.H.J. (2008). A flexible national living donor kidney exchange program taking advantage of a central histocompatibility laboratory: the Dutch model. Clinical Transplants, 69–73. Retrieved from http://hdl.handle.net/1765/17705