NSCLC is a highly heterogeneous malignancy with a poor prognosis. Treatment for NSCLC is currently based on a combination of pathological staging and histological classification. Recently, gene expression-based NSCLC profiling is proven a superior approach to stratify cancer cases with different prognosis and to sub-classify patients in respect of response to chemotherapy. The goal of the work described in this thesis is to explore the possible application of expression profiling in oncological practice.

NSCLC, gene expression, genetics, lung cancer
F.G. Grosveld (Frank) , J.N.J. Philipsen (Sjaak)
Erasmus University Rotterdam
Cancer Genomics Centre (CGC), Netherlands Bioinformatics Centre (NBIC), Netherlands Consortium for System Biology (NCSB), Netherlands Proteomics Centre (NPC)
Erasmus MC: University Medical Center Rotterdam

Hou, J. (2010, January 13). Gene Expression Profiling of Early Stage Non-Small Cell Lung Cancer. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/17731