Purpose: To investigate continuous distraction osteogenesis (DO) of the nasal bones in a rabbit model, and to compare data from this continuous DO study with data from a previously conducted discontinuous DO study. In addition, radiographic and ultrasonographic bone-fill scores were determined to investigate whether these scores provided reliable predictive value for the amount of new bone formation in the distraction area. Materials and Methods: Skeletally mature female New Zealand White rabbits were subjected to distraction of the nasal bones. A custom-made continuous distractor was used to perform automatic non-stop distraction. Bone data were obtained from radiography, ultrasonography, and microcomputed tomography. Data from this experiment were compared with data from a previous study on discontinuous distraction rhythms. Results: Ultrasonographic bone-fill scores correlated significantly to actual bone volume in contrast to radiographic bone-fill scores. Bone volume was significantly higher in the continuous DO group compared with the discontinuous DO groups. Conclusion: Continuous distraction resulted in accelerated osteogenesis compared with discontinuous distraction. Furthermore, bone-fill scores based on ultrasonography showed a significant correlation with actual bone volumes.

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doi.org/10.1016/j.joms.2008.08.016, hdl.handle.net/1765/18004
Journal of Oral and Maxillofacial Surgery
Erasmus MC: University Medical Center Rotterdam

Djasim, U., Wolvius, E., Bos, J., van Neck, H., & van der Wal, K. (2009). Continuous Versus Discontinuous Distraction: Evaluation of Bone Regenerate Following Various Rhythms of Distraction. Journal of Oral and Maxillofacial Surgery, 67(4), 818–826. doi:10.1016/j.joms.2008.08.016