The term 'coronary thrombosis' was derived from clinical and pathological observations on myocardial infarction made at least 80 years ago' and perhaps even earlier.'·} It was probably not until the 1930s that clinically manifest ischaemic heart disease in the form of myocardial infarction became a familiar condition rather than the unusual occurrence or even the rarity it had hitherto been. When the growing epidemic of clinical ischaemic heart disease prompted an increasing and concerted research programme after the Second World War, interest largely centred on the lipid nature of the atheromatous plaque and the contributions dietary fat intake and blood cholesterol levels make to it.

, , ,
Netherlands Heart Foundation, Dutch Thrombosis Foundation, Behringwerke AG (Germany), Dutch Ministry of Health and Ministry of Education, Netherlands Organization for Scientific Research
D.E. Grobbee (Diederick)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

van der Bom, A. (1997, April 2). Haemostasis and cardiovascular disease. Retrieved from