Hepatic encephalopathy (HE) is traditionally graded into four clinical stages of severity, ranging from lethargy, sleep and memory disturbances (grade 1) to coma (grade 4). In addition to the clinical grading of HE, a subclinical stage has been described. In subclinical hepatic encephalopathy (SHE)* patients with cirrhosis, regardless of its etiology, exhibit various quantifiable neuropsychological defects, but have a normal mental and neurological status on standard clinical examination.

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S.W. Schalm (Solko)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Guero Guillen, J. C. (1997, May 7). Subclinical hepatic encephalopathy: diagnosis, clinical implications, and intervention. Retrieved from http://hdl.handle.net/1765/18071