Regulation of prostate-specific antigen expression

Steroid hormones are widely distributed, cholesterol-derived, small hydrophobic molecules. They mediate a variety of biological functions, including tissue development, differentiation and homeostasis. Mammalian steroid hormones (androgens, glucocorticoids, mineralocorticoids, estrogens and progestins) exert their function by binding to the corresponding intracellular steroid hormone receptor. This binding triggers a complex set of molecular events, including protein-protein and protein-DNA interactions.