In the first part of this chapter an overview will be presented on the structural, histological and functional aspects of the normal human prostate. The second part describes the epidemiological and clinicopathological features of prostatic adenocarcinoma. Further, a state of the art of (cyto)genetic aberrations occurring in prostatic cancer is given. The third part of this introduction will discuss methodological aspects of this thesis, i.e., the development and methodology of non-isotopic in situ hybridization. Finally, the scope of this thesis will be presented.

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Nederlands Kankerbestrijding-Koningin Wilhelmina Fonds (projectnr. EUR 92-35)
Th.H. van der Kwast (Theo) , F.T.B. Bosman (Fré)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Alers, J. (1997, September 10). Interphase cytogenetics of prostatic adenocarcinoma. Retrieved from