We present a patient with a history of myelitis, who had a steroid refractory attack of CNS inflammatory demyelinating disease that developed into cerebral concentric sclerosis of Balo after plasma exchange. The acute inflammatory disease involved the spinal cord, a phenomenon rarely demonstrated. This patient fulfilled the McDonald criteria for multiple sclerosis. Plasmapheresis did not have a beneficial effect, but the patient stabilised at high EDSS after treatment with mitoxantron.

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doi.org/10.1016/j.jns.2008.12.030, hdl.handle.net/1765/18270
Journal of the Neurological Sciences
Erasmus MC: University Medical Center Rotterdam

Kreft, K., Mellema, J., & Hintzen, R. (2009). Spinal cord involvement in Balo's concentric sclerosis. Journal of the Neurological Sciences, 279(1-2), 114–117. doi:10.1016/j.jns.2008.12.030