This article reviews the microbiological diagnostic tests that are currently available for the detection of M pneumoniae, C pneumoniae, and Legionella spp; their clinical performance; and their future in the clinical microbiology laboratory. When implementing a strategy, a balance between performance criteria (sensitivity, specificity) and convenience criteria (clinical utility, turnaround time, and costs) will have to be defined. In the end, this should result in the optimization of clinical patient management.

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doi.org/10.1016/j.idc.2009.10.013, hdl.handle.net/1765/19432
Infectious Disease Clinics of North America
Erasmus MC: University Medical Center Rotterdam

te Witt, R., van Leeuwen, W., & van Belkum, A. (2010). Specific Diagnostic Tests for Atypical Respiratory Tract Pathogens. Infectious Disease Clinics of North America (Vol. 24, pp. 229–248). doi:10.1016/j.idc.2009.10.013