Introduction and hypothesis: Estimation on prevalence and distribution of pelvic organ prolapse (POP) signs in a general female population is difficult. We therefore developed and validated a prediction model and prognostic instrument. Methods: Questionnaires were sent to a general female population (45-85 years). A random sample underwent vaginal examination for POP (POPQ). A prediction model was developed using multivariate analysis and validated in a subgroup of participants. Results: Positive questionnaire-response rate was 46.8% (1,397 of 2,979). From the questionnaire group, 649 women were vaginally examined (46.5%). Prevalence of clinically relevant POP was 21%. Multivariate analysis demonstrated significantly higher odds ratios on the report of vaginal bulging, parity ≥2 and a mother with POP. The receiver operating characteristic curve showed areas under the curve of 0.672 and 0.640. Conclusions: The prevalence of POP at or beyond the hymen could be estimated in a general female population using our prediction model with 17 questions and our POP score chart with eight questions.

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International Urogynecology Journal: and pelvic floor dysfunction
Erasmus MC: University Medical Center Rotterdam

Slieker-ten Hove, M., Pool-Goudzwaard, A., Eijkemans, R., Steegers-Theunissen, R., Burger, C., & Vierhout, M. (2009). Erratum: Prediction model and prognostic index to estimate clinically relevant pelvic organ prolapse in a general female population (International Urogynecology Journal and Pelvic Floor Dysfunction DOI: 10.1007/s00192-009-0903- 0). International Urogynecology Journal: and pelvic floor dysfunction, 21(3), 387–388. doi:10.1007/s00192-009-1072-x