2010-05-21
Congenital Diaphragmatic Hernia: A pulmonary vascular point of view
Publication
Publication
Congenitale hernia diaphragmatica: Over de pulmonale circulatie
Treatment of pulmonary hypertension (PH) in neonates is a major challenge on the intensive care unit and involves high morbidity and mortality. However we have gained considerable insights into the pathophysiology of PH leading to an increasing number of possible treatment targets. Translation of these novel targets into clinical application requires multi-centre randomized controlled trials. Furthermore, considering the underlying pathology is important in therapy choice. New therapies will not only target vasodilatation, but also reduce vascular remodeling and enhance postnatal lung development. This review provides an overview of currently available drugs and promising new targets in the treatment of PH in newborns.
Additional Metadata | |
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FSC Mixed Sources | |
D. Tibboel (Dick) | |
Erasmus University Rotterdam | |
hdl.handle.net/1765/19546 | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
van der Horst, I. W. J. M. (2010, May 21). Congenital Diaphragmatic Hernia: A pulmonary vascular point of view. Retrieved from http://hdl.handle.net/1765/19546 |
Additional Files | |
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Stellingen Irene van der Horst behorende bij CDH a pulmonary vascular point of view.pdf , 99kb | |
3101_Horst, Irene Wilhelmina Johanna Maria van der.jpg Cover Image , 21kb |