The recently developed genome-wide association study (GWAS) design enables the identification of genes specifically associated with economic outcomes such as occupational and other choices. This is a promising new approach for economics research which we aim to apply to the choice for entrepreneurship. However, due to multiple testing issues, very large sample sizes are needed to differentiate between true and false positives. For a GWAS on entrepreneurship, we expect that a sample size of at least 30,000 observations is required.

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ERIM Top-Core Articles
Small Business Economics: an entrepreneurship journal
Erasmus Research Institute of Management

Koellinger, P., van der Loos, M., Groenen, P., Thurik, R., Rivadeneira Ramirez, F., & van Rooij, F. (2010). Genome-wide association studies in economics and entrepreneurship research: promises and limitations. Small Business Economics: an entrepreneurship journal, 35(1), 1–18. Retrieved from