Early and long-term morbidity after total laryngopharyngectomy
European Archives of Oto-Rhino-Laryngology , Volume 267 - Issue 9 p. 1437- 1444
To determine the early and long-term morbidity of patients treated with a total laryngopharyngectomy and reconstruction using a jejunum interposition or gastric pull-up procedure. It is a retrospective study; and it is conducted in tertiairy referral center. Sixty-three patients were included in whom 70 reconstructions were performed (51 jejunum interpositions and 19 gastric pull-up procedures) between 1990 and 2007. The studied parameters were success rate of the reconstruction, early and long-term complication rate, and functional outcome including quality of life. Subjective quality of life analysis was determined by two questionnaires: the EORTC Quality of Life Questionnaire (QLQ)-C30 Dutch version 3.0, and the EORTC-Head and Neck (H & N 35). The success rates were 84 and 74%, respectively. The procedures were associated with a high complication rate (63% after jejunum interposition and 89% after gastric pull-up), and a lengthy rehabilitation. Surviving patients were found to have a good long-term quality of life. Complete oral intake was achieved in 97%, and speech rehabilitation in 95%. These procedures are associated with significant morbidity, high complication rates, lengthy rehabilitation, but a good long-term quality of life.
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|European Archives of Oto-Rhino-Laryngology|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Keereweer, S, de Wilt, J.H.W, Sewnaik, A, Meeuwis, C.A, Tilanus, H.W, & Kerrebijn, J.D.F. (2010). Early and long-term morbidity after total laryngopharyngectomy. European Archives of Oto-Rhino-Laryngology, 267(9), 1437–1444. doi:10.1007/s00405-010-1244-9