The objectives of this thesis are to: 1. Compare the induced CDH in rats with the human situation and other available animal models. 2. Describe the morphological characteristics of the developing rat lung and diaphragm in congenital diaphragmatic hernia compared with controls. 3. Evaluate the suitability of this model in testing different ventilatory modes and the subsequent reaction of the CDH lung from a biochemical and histological point of view.

Additional Metadata
Keywords childhood, congenital diaphragmatic hernia, infancy, rat, thorax
Promotor D. Tibboel (Dick) , B.F. Lachmann (Burkhard)
Publisher Erasmus University Rotterdam
Sponsor Physio B. V. te Haarlem, Roche Nederland B.V. te Mijdrecht, Siemens Nederland N. V. te Den Haag
Persistent URL
Tenbrinck, R. (1995, May 31). Induced congenital diaphragmatic hernia: a model in rats. Erasmus University Rotterdam. Retrieved from