Oropharyngeal Cancer (Chapter 2) Good tumor control but late-side effects occur e.g. dysphagia. Quality of Life: Dysphagia (Chapters 3-6) Dose-effects relationships in base of tongue, tonsillar fossa and nasopharyngeal cancer are found for swallowing problems. Quality of Lfe: Trismus (Chapter 7) Dose-effects relationships in base of tongue and tonsillar fossa are found for trismus problems. Brachytherapy (Chapters 8-10) Patient treated by brachyhterapy have better local control, disease-free survival and overal survival than those treated with EBRT. Also BT patients were found to have fewer swallowing problems compared with the non-BT group of patients. Hyperbaric Oxygen (Chapter 11) A great benefit for the quality of life of patients was seen in patients who were randomized for hyperbaric oxygen after radiotherapy. A significant difference of different aspects of quality of life was seen for H&N35 ‘swallowing problems’, H&N35 ‘sticky saliva’, H&N35 ‘dry mouth’, visual analogue scale (VAS) ‘Dry mouth’, PSS ‘eating in public’ and VAS ‘pain in mouth’ in favor of the hyperbaric oxygen group. Non-Rigid Registration / Atlas-Based Auto-Segmentation (Chapters 12-14) Non-rigid registration method is a powerful tool to accurately assess local shape and position changes in HNC patients. When using ABAS, edited auto-contours were somewhat more in concordance with the corresponding levels of this atlas as opposed to the originally contoured levels.

Additional Metadata
Keywords FEES, atlas based auto segmentation, autocontouring, brachytherapy, dysphagia, hyperbaric oxygen, nasopharynx, non-rigid registrations, oropharynx, quality of life, swallowing problems, trismus, xerostomia
Promotor P.C. Levendag (Peter)
Publisher Erasmus University Rotterdam
Sponsor Accuray EIMEA, Elekta-CMS Software,Eli Lilly, Instituut voor Hyperbare Geneeskunde, Nucletron, Toko Morodadi, Salatiga & Toko Ekonomi, Magelang
ISBN 978-90-90-25839-3
Persistent URL hdl.handle.net/1765/21912
Citation
Teguh, D.N. (2010, December 22). Late Morbidity (Dysphagia) in Head and Neck Cancer after Radiotherapy using various Treatment Techniques. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/21912