BACKGROUND: Stroke has a major impact on survivors. Our study was designed to describe the mental status and health-related quality of life (HRQoL) in long-term survivors of TIA or minor ischaemic stroke (MIS) and evaluate associations of mental and physical factors with HR-QoL. METHODS: A random sample of the 10-year survivors of the Dutch TIA Trial (DTT) and the dutch participants of the European Atrial Fibrillation Trial (EAFT) were interviewed by postal questionnaire (n = 468) and at home (n = 198). Demographic data, mental health status (depression (CES-D), cognition (CAMCOG)), and health perception (SF-36 and Euroqol) were measured. RESULTS: 198 long-term survivors were included; mean age was 72.5 (SD 8.7 years), 22% was depressed (CES-D > or = 16) and 15% had cognitive dysfunction (CAMCOG < 80). The overall HR-QoL did not differ much from the norm population. Physical disability, occurrence of a major stroke and comorbidity of locomotion or the heart were independently associated with a low health perception. CONCLUSIONS: Despite varying amounts of disability, the majority of long-term survivors of a TIA or MIS rated their quality of life as rather good. Physical factors, rather than mental status were independently related to a decrease in perceived health.

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Keywords Aged, Aged, 80 and over, Brain Ischemia/epidemiology/mortality/*physiopathology/*psychology, Disabled Persons/statistics & numerical data, Female, Health Status, Humans, Longitudinal Studies, Male, Quality of Life, Questionnaires, Regression Analysis, Retrospective Studies, Survivors, cerebral ischaemia, comorbidity, health-related quality of life, mental status
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Journal Journal of Neurology
van Wijk, I, Gorter, J.W, Lindeman, E, Kappelle, L.J, van Gijn, J, Koudstaal, P.J, & Algra, A. (2007). Mental status and health-related quality of life in an elderly population 15 years after limited cerebral ischaemia. Journal of Neurology, 254(8), 1018–1025. doi:10.1007/s00415-006-0480-9