This thesis comprises studies of gas transfer in the lungs during mechanical ventilation, which have been obtained in healthy pigs. The objectives of this thesis were: I) to adapt the breath-holding teclmique, as used during spontaneous breathing for estimation of gas transfer, to conditions of mechanical ventilation; and 2) to evaluate the effect of changes in lung volume on pulmonary gas transfer and capillary blood volume.

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NWO, Trustfonds Erasmus University Rotterdam, Radiometer Nederland BV, Hoek Loos (Schiedam), Jaeger Nederland B.V. (Breda)
A. Versprille (Adrian)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

te Nijenhuis, F. (1996, September 18). Carbon monoxide transfer in pig lungs during mechanical ventilation. Retrieved from