Malformations of cortical development (MCD) are a group of disorders characterized by a congenital abnormal structure of the cerebral cortex. In general, malformations are defined as structural abnormalities caused by a disturbance in cell organization or function within a tissue type. When a disturbance results in an abnormal structure of the cerebral cortex we call this: malformations of cortical development. MCD are heterogeneous as a group, as they include several different structural abnormalities, and they have a diverse array of causes, both genetic and environmental.

Additional Metadata
Keywords MCD, congenital malformations, disorders, malformations of the cerebral cortex
Promotor W.F.M. Arts (Willem Frans) , F.G. Grosveld (Frank)
Publisher Erasmus University Rotterdam
Sponsor Erasmus MC Rotterdam,UCB Pharma B.V., Cyberonics Europe N.V., Sanofi-Aventis Netherlands B.V.
ISBN 978-90-5335-305-9
Persistent URL
de Wit, M.C.Y. (2010, September 10). Malformations of the Human Cerebral Cortex: patterns and causes. Erasmus University Rotterdam. Retrieved from