Chromosomal localization of the human Thy-1 gene.
We have isolated the gene coding for human Thy-1. Introduction of this gene into HeLa cells by DNA-mediated transfer results in the expression of Thy-1 antigen on the cell surface. Chromosomal mapping of the Thy-1 gene by hybridization to metaphase chromosomes and Southern blots of DNA from hybrid cells indicate that the Thy-1 gene is located on the long arm of chromosome 11.
|Keywords||*Chromosomes, Human, 6-12 and X, 0 (Antigens, Surface), 0 (Antigens, Thy-1), Antigens, Surface/*genetics, Antigens, Thy-1, Cloning, Molecular, Gene Expression Regulation, Genes, Structural, Hela Cells, Human, Nucleic Acid Hybridization, Support, Non-U.S. Gov't|
|Journal||Proceedings of the National Academy of Sciences of the United States of America|
van Rijs, J, Giguere, V, Hurst, J, van Agthoven, A.J, Goyert, S, Grosveld, F.G, & Geurts van Kessel, A.H.M. (1985). Chromosomal localization of the human Thy-1 gene. Proceedings of the National Academy of Sciences of the United States of America, 82, 5832–5835. Retrieved from http://hdl.handle.net/1765/2387