Cushing syndrome as the presenting symptom of a malignant renal tumor in children is rare. We report the first case of paraneoplastic Cushing syndrome due to a Wilms tumor, in which clinical and biological signs of hypercortisolism regressed during preoperative chemotherapy. Additionally, we reviewed the literature on paraneoplastic Cushing syndrome secondary to pediatric renal tumors.

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Pediatric Blood & Cancer
Erasmus MC: University Medical Center Rotterdam

Segers, H., van der Heyden, J., van den Akker, E., de Krijger, R., Zwaan, M., & van den Heuvel-Eibrink, M. (2009). Cushing syndrome as a presenting symptom of renal tumors in children. Pediatric Blood & Cancer, 53(2), 211–213. doi:10.1002/pbc.22021