Prediction model and prognostic index to estimate clinically relevant pelvic organ prolapse in a general female population
International Urogynecology Journal: and pelvic floor dysfunction , Volume 20 - Issue 9 p. 1013- 1021
Introduction and hypothesis: Estimation on prevalence and distribution of pelvic organ prolapse (POP) signs in a general female population is difficult. We therefore developed and validated a prediction model and prognostic instrument. Methods: Questionnaires were sent to a general female population (45-85 years). A random sample underwent vaginal examination for POP (POPQ). A prediction model was developed using multivariate analysis and validated in a subgroup of participants. Results: Positive questionnaire-response rate was 46.8% (1,397 of 2,979). From the questionnaire group, 649 women were vaginally examined (46.5%). Prevalence of clinically relevant POP was 21%. Multivariate analysis demonstrated significantly higher odds ratios on the report of vaginal bulging, parity ≥2 and a mother with POP. The receiver operating characteristic curve showed areas under the curve of 0.672 and 0.640. Conclusions: The prevalence of POP at or beyond the hymen could be estimated in a general female population using our prediction model with 17 questions and our POP score chart with eight questions.
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|International Urogynecology Journal: and pelvic floor dysfunction|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Slieker-ten Hove, M.C.P, Pool-Goudzwaard, A.L, Eijkemans, M.J.C, Steegers-Theunissen, R.P.M, Burger, C.W, & Vierhout, M.E. (2009). Prediction model and prognostic index to estimate clinically relevant pelvic organ prolapse in a general female population. International Urogynecology Journal: and pelvic floor dysfunction, 20(9), 1013–1021. doi:10.1007/s00192-009-0903-0