Aspergillus mastoidits and skull-base osteomyelitis are extremely rare, even in immunocompromised patients. We report a case of an 81-year-old immunocompetent man, who underwent a mastoidectomy because of unexplained, progressive otalgia in spite of a noninflamed and air-containing middle-ear space. Histopathology yielded Aspergillus fumigatus. When confronted with otitis with an unexpected clinical course a high index of suspicion is required to facilitate early diagnosis and appropriate therapy of a potential lethal Aspergillus infection, even in immunocompetent patients. This seems to be more so in older patients with an open middle-ear cavity and/or when there is facial nerve involvement.

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doi.org/10.1007/s00405-008-0877-4, hdl.handle.net/1765/24181
European Archives of Oto-Rhino-Laryngology
Erasmus MC: University Medical Center Rotterdam

van Tol, A., & van Rijswijk, J. B. (2009). Aspergillus mastoiditis, presenting with unexplained progressive otalgia, in an immunocompetent (older) patient. European Archives of Oto-Rhino-Laryngology, 266(10), 1655–1657. doi:10.1007/s00405-008-0877-4