Transcriptional Regulation of Multi-Gene Loci: Multi-Level Control.
Trends in Genetics , Volume 9 - Issue 4 p. 134- 137
Recent studies indicate that different levels of control operate within multigene loci. In addition to regulatory sequences immediately flanking the genes, there are also elements that act over long distances on more than one gene. Competition for these elements among genes can influence both the level and timing of gene expression during development.
|*Gene Expression Regulation, *Multigene Family, *Regulatory Sequences, Nucleic Acid, *Transcription, Genetic, Animals, Genes, Regulator/physiology, Human, Mice, Support, Non-U.S. Gov't|
|Trends in Genetics|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Dillon, N.O, & Grosveld, F.G. (1993). Transcriptional Regulation of Multi-Gene Loci: Multi-Level Control. Trends in Genetics, 9(4), 134–137. doi:10.1016/0168-9525(93)90208-Y