This thesis addresses the major issues encountered in the diagnosis and treatment of adult elbow dislocation. Firstly, a literary review (Chapters Five and Eight) makes it clear that there is much uncertainty regarding trauma mechanism, biomechanics, and even anatomy (Chapter Two). Furthermore, an overview of the treatment options indicates that there is no uniformity in the treatment modalities applicable to elbow dislocation (Chapter Six). And last but not least, there is no Dutch questionnaire which can be used to determine the outcome of treatment. In order to address these issues, this thesis presents the validation of a new Dutch questionnaire (Chapters Three and Four) and includes the publication of protocols and a trial management system for the performance of two unique, prospective multicenter studies (Chapters Seven and Ten) that will evaluate the outcome of treatment modalities with respect to traumatic elbow dislocation.