Molecular aspects of Moraxella catarrhalis pathogenesis

Our understanding of the factors facilitating M. catarrhalis pathogenesis is far from complete. However, it has already been shown that a complex, multifactorial interaction, involving a wide range of bacterium- and host-specific macromolecules, takes place between M. catarrhalis and its human host. Currently known virulence factors include OMPs, LOS, and metabolic pathways, which are involved in adhesion, invasion, biofilm formation, modulation of the host immune system, and acquisition of nutrients.

• View at Publisher
• View at Pubmed
• View at Scopus
• View at Web of Science