Regulatory T cells (Treg) offer potential for improving long-term outcomes in cell and organ transplantation. The non-human primate model is a valuable resource for addressing issues concerning the transfer of Treg therapy to the clinic. Herein, we discuss the properties of non-human primate Treg and prospects for their evaluation in allotransplantation and xenotransplantation.

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Keywords Non-human primates, Regulatory T cells, Transplantation, Xenotransplantation
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Journal Transplantation
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Dons, E.M, Raimondi, G, Cooper, D.K.C, & Thomson, A.W. (2010). Non-human primate regulatory T cells: Current biology and implications for transplantation. Transplantation, 90(8), 811–816. doi:10.1097/TP.0b013e3181ebf782