Regulatory T cells (Treg) offer potential for improving long-term outcomes in cell and organ transplantation. The non-human primate model is a valuable resource for addressing issues concerning the transfer of Treg therapy to the clinic. Herein, we discuss the properties of non-human primate Treg and prospects for their evaluation in allotransplantation and xenotransplantation.

, , ,
doi.org/10.1097/TP.0b013e3181ebf782, hdl.handle.net/1765/27310
Transplantation
Erasmus MC: University Medical Center Rotterdam

Dons, E., Raimondi, G., Cooper, D., & Thomson, A. (2010). Non-human primate regulatory T cells: Current biology and implications for transplantation. Transplantation, 90(8), 811–816. doi:10.1097/TP.0b013e3181ebf782