2010-05-01
Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma
Publication
Publication
Leukemia Research: clinical and laboratory studies , Volume 34 - Issue 5 p. 677- 681
We have used copy number variation (CNV) analysis with SNP mapping arrays for miRNA-15a and miRNA-16-1 expression analysis in patients with multiple myeloma (MM) with or without deletion of chromosome 13q14. MiRNA-15a and miRNA-16 display a range of expression patterns in MM patients, independent of the chromosome 13 status. These findings suggest that genes other than miR-15a and miR-16 may explain the prognostic significance of 13q14 deletions.
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| doi.org/10.1016/j.leukres.2009.10.026, hdl.handle.net/1765/27795 | |
| Leukemia Research: clinical and laboratory studies | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Corthals, S., Jongen-Lavrencic, M., de Knegt, Y., Peeters, J., Beverloo, B., Lokhorst, H., & Sonneveld, P. (2010). Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma. Leukemia Research: clinical and laboratory studies, 34(5), 677–681. doi:10.1016/j.leukres.2009.10.026 |
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