Laparoscopic donor nephrectomy (LDN) is less traumatic and painful than the open approach, with shorter convalescence time. Hand-assisted retroperitoneoscopic (HARP) donor nephrectomy may have benefits, particularly in left-sided nephrectomy, including shorter operation and warm-ischemia time (WIT) and improved safety. We evaluated outcomes of HARP alongside LDN. From July 2006 to May 2008, 20 left-sided HARP procedures and 40 left-sided LDNs were performed. Intra and postoperative data were prospectively collected and analysis on outcome of both techniques was performed. More female patients underwent HARP compared to LDN (75% vs. 40%, P = 0.017). Other baseline characteristics were not significantly different. Median operation time and WIT were shorter in HARP (180 vs. 225 min, P = 0.002 and 3 vs. 5 min, P = 0.007 respectively). Blood loss did not differ (200 ml vs.150 ml, P = 0.39). Intra and postoperative complication rates for HARP and LDN (respectively 10% vs. 25%, P = 0.17 and 5% vs. 15%, P = 0.25) were not significantly different. During median follow-up of 18 months estimated glomerular filtration rates in donors and recipients and graft- and recipient survival did not differ between groups. Hand-assisted retroperitoneoscopic donor nephrectomy reduces operation and warm ischemia times, and provides at least equal safety. Hand-assisted retroperitoneoscopic may be a valuable alternative for left-sided LDN.

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Transplant International
Erasmus MC: University Medical Center Rotterdam

Dols, L.F.C, Kok, N.F.M, Terkivatan, T, Tran, T.C.K, Alwayn, I.P.J, Weimar, W, & IJzermans, J.N.M. (2010). Optimizing left-sided live kidney donation: Hand-assisted retroperitoneoscopic as alternative to standard laparoscopic donor nephrectomy. Transplant International, 23(4), 358–363. doi:10.1111/j.1432-2277.2009.00990.x