Purpose: To examine the feasibility, reliability, and validity of the newly developed EQ-5D-Y. Methods: The EQ-5D-Y was administered in population samples of children and adolescents in Germany, Italy, South Africa, Spain, and Sweden. Percentages of missing values and reported problems were calculated. Test-retest reliability was determined. Spearman's rank correlation coefficients with other generic measures of HRQOL were calculated. Known groups' validity was examined by comparing groups with a priori expected differences in HRQOL. Results: Between 91 and 100% of the respondents provided valid scorings. Sweden had the lowest proportion of reported problems (1-24.9% across EQ-5D-Y dimensions), with the highest proportions in South Africa (2.8-47.3%) and Italy (4.3-39.0%). Percentages of agreement in test-retest reliability ranged between 69.8 and 99.7% in the EQ-5D-Y dimensions; Kappa coefficients were up to 0.67. Correlation coefficients with other measures of self-rated health indicated convergent validity (up to r = - 0.56). Differences between groups classified according to presence of chronic conditions, self-rated overall health and psychological problems provided preliminary evidence of known groups' validity. Conclusions: Results provide preliminary evidence of the instrument's feasibility, reliability and validity. Further study is required in clinical samples and for possible future applications in economic analyses.

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doi.org/10.1007/s11136-010-9649-x, hdl.handle.net/1765/28218
Quality of Life Research
Erasmus MC: University Medical Center Rotterdam

Ravens-Sieberer, U, Wille, N, Badia, X, Bonsel, G.J, Burström, K, Cavrini, G, … Greiner, W. (2010). Feasibility, reliability, and validity of the EQ-5D-Y: Results from a multinational study. Quality of Life Research, 19(6), 887–897. doi:10.1007/s11136-010-9649-x