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C. O'Dushlaine (Colm), R. McQuillan (Ruth), M.E. Weale (Michael), D.J.M. Crouch (Daniel), A. Johansson (Åsa), Y.S. Aulchenko (Yurii), C.S. Franklin (Christopher), O. Polasek (Ozren), C. Fuchsberger (Christian), A. Corvin (Aiden), et al. A.A. Hicks (Andrew), V. Vitart (Veronique), C. Hayward (Caroline), S.H. Wild (Sarah), T. Meitinger (Thomas), P. Tikka-Kleemola (Päivi), U. Gyllensten (Ulf), A.F. Wright (Alan), H. Campbell (Harry), P.P. Pramstaller (Peter Paul), I. Rudan (Igor) and J.F. Wilson (James)

2010-11-01

Genes predict village of origin in rural Europe

Publication

Publication

European Journal of Human Genetics , Volume 18 - Issue 11 p. 1269- 1270

The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.

Additional Metadata
Keywords genome-wide genotyping, population structure, principal components
Persistent URL doi.org/10.1038/ejhg.2010.92, hdl.handle.net/1765/28257
Journal European Journal of Human Genetics
Note Free full text at PubMed
Organisation Erasmus MC: University Medical Center Rotterdam
Citation
O'Dushlaine, C., McQuillan, R., Weale, M., Crouch, D., Johansson, Å., Aulchenko, Y., … Wilson, J. (2010). Genes predict village of origin in rural Europe. European Journal of Human Genetics, 18(11), 1269–1270. doi:10.1038/ejhg.2010.92
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