Long-term followup of temporomandibular joint involvement in juvenile idiopathic arthritis
Objective. Temporomandibular joint (TMJ) involvement is a frequent feature in cross-sectional prevalence studies among patients with juvenile idiopathic arthritis (JIA). In this followup study, patients were reviewed after 5 years to study the course of TMJ involvement in relation to disease characteristics. Methods. Children with JIA from a previous study on TMJ involvement were included. A rheumatologic evaluation including the 6 parameters of the JIA core set and an orthodontic evaluation including an orthopantomogram (OPT) were performed. OPTs were scored according to Rohlin's grading system (grades 0-5). Results. The overall prevalence of patients with condylar alterations decreased from 49% to 40%. Improvement of the alterations was seen in 69% of the initially affected condyles, and consequently improvement was seen in 83% of the initially affected patients. Normalization of the alterations was seen in 67% of the improved condyles, and consequently in 44% of the patients. This proves that the condyle has a regenerative capacity. Improvement was related to low disease activity and a less extensive therapeutic regimen. Conclusion. In patients with JIA, condylar alterations can improve and even regenerate. Condylar improvement is associated with a low disease activity.
|Persistent URL||dx.doi.org/10.1002/art.23532, hdl.handle.net/1765/28896|
|Journal||Arthritis Care & Research|
|Note||Free full text at PubMed|
Twilt, M, Schulten, A.J.M, Verschure, F, Wisse, L, Prahl-Andersen, B, & van Suijlekom-Smit, L.W.A. (2008). Long-term followup of temporomandibular joint involvement in juvenile idiopathic arthritis. Arthritis Care & Research, 59(4), 546–552. doi:10.1002/art.23532