Hepatitis C virus (HCV) genomes exhibit high nucleotide sequence diversity. In this study, we performed complete genome sequence analysis of 11 HCV genotype 6 samples from Vietnam and Thailand. We identified nine HCV complete genomes belonging to subtypes 6a (D9), 6e (D42 and D88), 6f (TH52), 6i (TH24), 6l (D33), 6n (TH22 and TH31) and 6o (D85). Phylogenetic analysis of the core/E1 and NS5B regions from unclassified genotype 6 isolates from Asian immigrants in Canada revealed that two other viruses (D49 and D83) could be classified as novel candidates of HCV subtypes 6t and 6u.

doi.org/10.1099/vir.0.83593-0, hdl.handle.net/1765/28942
Journal of General Virology
Erasmus MC: University Medical Center Rotterdam

Noppornpanth, S., Poovorawan, Y., Lien, T. X., Smits, S., Osterhaus, A., & Haagmans, B. (2008). Complete genome analysis of hepatitis C virus subtypes 6t and 6u. Journal of General Virology, 89(5), 1276–1281. doi:10.1099/vir.0.83593-0