A total of 11 patients with recurrent rectal cancer who had been previously irradiated were treated with preoperative reirradiation (median dose 30 Gy), surgery and IORT. This treatment was related with high morbidity, a short pain-free survival (5 months) and poor local control (27% after 3 years), although some patients have long-term distant control and survival.

IORT, Radiotherapy, Rectal cancer, Recurrent, Reirradiation, Surgery
dx.doi.org/10.1016/j.radonc.2008.02.021, hdl.handle.net/1765/29303
Radiotherapy & Oncology
Erasmus MC: University Medical Center Rotterdam

Vermaas, M, Nuyttens, J.J.M.E, Ferenschild, F.T.J, Verhoef, C, Eggermont, A.M.M, & de Wilt, J.H.W. (2008). Reirradiation, surgery and IORT for recurrent rectal cancer in previously irradiated patients. Radiotherapy & Oncology, 87(3), 357–360. doi:10.1016/j.radonc.2008.02.021