Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity
Vaccine , Volume 26 - Issue 17 p. 2056- 2057
In this study we present new data showing strain-specific differences on the effect of commercially available probiotic drinks in an EAE rat autoimmune model for multiple sclerosis. In this particular model, we conclude that these drinks do not enhance but rather suppress the disease. We suggest that conclusions on probiotics are limited to specific strains and models and not generalised. We further suggest that physiological use (normal route, normal dose, normal growth phase, specific strain or substrain/species) is studied in all cases, so as not to overwhelm (high dose) or circumvent natural immune processing.
|EAE, Lactobacilli, Multiple sclerosis, Probiotics, Rat|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Maassen, C.B.M, & Claassen, H.J.H.M. (2008). Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity. Vaccine, 26(17), 2056–2057. doi:10.1016/j.vaccine.2008.02.035