In this concise overview, we discuss recent findings concerning a distinct subgroup of acute myeloid/T-lymphoid leukemia. We describe how we identified these leukemias in multiple cohorts of acute myeloid leukemia (AML) using a combination of gene expression profiling and additional analytic approaches, and how we obtained insight in possible mechanisms leading to their phenotype.

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doi.org/10.1016/j.bcmd.2007.10.006, hdl.handle.net/1765/30066
Blood Cells, Molecules and Diseases
Erasmus MC: University Medical Center Rotterdam

Wouters, B., Koss, C., & Delwel, R. (2008). Gene expression profiling for improved dissection of acute leukemia: A recently identified immature myeloid/T-lymphoid subgroup as an example. Blood Cells, Molecules and Diseases (Vol. 40, pp. 395–400). doi:10.1016/j.bcmd.2007.10.006