Preclinical evaluation of anti-rheumatic drugs in a non-human primate model of arthritic disease
Drug Discovery Today: Disease Models , Volume 5 - Issue 2 p. 89- 95
There is a reluctance in preclinical rheumatoid arthritis research to consider non human primates as useful disease models in translational research and for the development of anti-rheumatic drugs. This review pleads for the usage of nonhuman primates disease models to bridge the wide immunological gap between rodents and the RA patient.
|Drug Discovery Today: Disease Models|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Vierboom, M.P.M, Breedveld, E, & 't Hart, B.A. (2008). Preclinical evaluation of anti-rheumatic drugs in a non-human primate model of arthritic disease. Drug Discovery Today: Disease Models (Vol. 5, pp. 89–95). doi:10.1016/j.ddmod.2008.06.003