Multiple sclerosis (MS) is a leading non-traumatic cause of disability in young adults. It is a chronic neurological disorder characterized primarily by central nervous system (CNS) inflammation, myelin loss, and axonal pathology, resulting in progressive neurological dysfunction. Initially, inflammation is transient and partial remyelination occurs. MS is presumed to be an autoimmune disorder arising from complex interactions of both environmental and genetic factors.

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R.Q. Hintzen (Rogier)
Erasmus University Rotterdam
Biogen idec International B.V., Boehringer Ingelheim B.V., Erasmus University Rotterdam, J.E. Juriaanse Stichting, Novaritis Pharma B.V., Sanofi-avenis Netherlands B.V., Stichting MS Research
Erasmus MC: University Medical Center Rotterdam

Jafari, N. (2012, January 20). Risk Factors in Cause and Course of Multiple Sclerosis. Erasmus University Rotterdam. Retrieved from