During deep hyperthermia treatment, patient pain complaints due to heating are common when maximizing power. Hence, there exists a good rationale to investigate whether the locations of predicted SAR peaks by hyperthermia treatment planning (HTP) are correlated with the locations of patient pain during treatment. A retrospective analysis was performed, using the treatment reports of 35 patients treated with deep hyperthermia controlled by extensive treatment planning. For various SAR indicators, the average distance from a SAR peak to a patient discomfort location was calculated, for each complaint. The investigated V01 closest(i.e. the part of the 0.1th SAR percentile closest to the patient complaint) performed the best, and leads to an average distance between the SAR peak and the complaint location of 3.9 cm. Other SAR indicators produced average distances that were all above 10 cm. Further, the predicted SAR peak location with V0.1provides a 77% match with the region of complaint. The current study demonstrates that HTP is able to provide a global indication of the regions where hotspots during treatment will most likely occur. Further development of this technology is necessary in order to use HTP as a valuable toll for objective and advanced SAR steering. The latter is especially valid for applications that enable 3D SAR steering.

doi.org/10.1088/0031-9155/56/2/010, hdl.handle.net/1765/31559
Physics in Medicine and Biology
Erasmus MC: University Medical Center Rotterdam

Canters, R., Franckena, M., van der Zee, J., & van Rhoon, G. (2011). Optimizing deep hyperthermia treatments: Are locations of patient pain complaints correlated with modelled SAR peak locations?. Physics in Medicine and Biology, 56(2), 439–451. doi:10.1088/0031-9155/56/2/010