This thesis consists of two parts. The first part deals with an increasingly important area of first and early second trimester (<14 weeks) normal and abnmmal fetal sonoanatomy and its validity and impact in the early diagnosis of fetal anomalies in a high-risk population. The second part of the thesis focuses on the clinical genetic aspects of fetal anomaly scanning with emphasis on the second half of gestation. Single fetal anomalies diagnosed by ultrasound may be associated with other and often minor anomalies. which pre- or postnatally may be identified as exogenic or genetic syndromes with specific recurrence risks. This will have important implications for genetic counseling

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M.F. Niermeijer (Martinus) , J.W. Wladimiroff (Juriy)
Erasmus University Rotterdam , Eburon, Delft
Erasmus MC: University Medical Center Rotterdam

den Hollander, N. (2002, January 9). Sonographic assessment of normal and abnormal fetal development; early and late aspects. Retrieved from