2008-05-01
Recent advances in the genetics of dementia with Lewy bodies
Publication
Publication
Current Neurology and Neuroscience Reports , Volume 8 - Issue 3 p. 187- 189
In the past few years, mutation's have bee identified in the genes encoding α-synuclein, leucine-rich repeat kinase 2, and glucocerebrosidase in some patients with dementia with Lewy bodies (DLB). Furthermore, a novel locus for familial DLB has been mapped to chromosome 2q35-q36. Collectively, these discoveries highlight a substantial overlap between the known genetic determinants of Parkinson's disease and DLB, as well as the presence of profound etiologic heterogeneity in Lewy body disorders. Copyright
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| doi.org/10.1007/s11910-008-0030-1, hdl.handle.net/1765/32332 | |
| Current Neurology and Neuroscience Reports | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Bonifati, V. (2008). Recent advances in the genetics of dementia with Lewy bodies. Current Neurology and Neuroscience Reports (Vol. 8, pp. 187–189). doi:10.1007/s11910-008-0030-1 |
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