Background: We examined the effectiveness of a structured collaboration in general practice between a practice nurse, a peer health educator, the general practitioner (GP) and a GP assistant in providing intensified preventive care for patients at high risk of developing cardiovascular diseases. DESIGN: A randomized controlled trial in three healthcare centres (18 GPs) in deprived neighbourhoods of two major Dutch cities. Methods: Two hundred seventy-five high-risk patients (30-70 years) from various ethnic groups were randomized to intervention (n=137) or usual care group (n=138). We determined group differences in outcomes [10-year absolute risk (Framingham risk equation), blood pressure, lipids and body mass index] at 12-month follow-up. Results: The 10-year absolute risk was reduced by 1.76% (standard error: 0.81) in intervention and by 2.27% (standard error: 0.69) in usual care group; the difference in mean change was 0.88% [95% confidence interval: -1.16 to 2.93]. In both groups significant reductions were observed in the following individual risk factors: total cholesterol, total cholesterol/high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol, with no relevance between group differences. Conclusion: The cardiovascular risk profile of intervention and control patients improved after 1-year follow-up. However, no extra effect of the structured preventive care on the risk for cardiovascular diseases was achieved.

Cardiovascular risk, Deprived neighbourhoods, General practice, Practice nurse, Secondary prevention
dx.doi.org/10.1097/HJR.0b013e3282fceac2, hdl.handle.net/1765/32379
European Journal of Cardiovascular Prevention & Rehabilitation
Erasmus MC: University Medical Center Rotterdam

El Fakiri, F, Bruijnzeels, M.A, Uitewaal, P.J.M, Frenken, R.A.A, Berg, M, & Hoes, A.W. (2008). Intensified preventive care to reduce cardiovascular risk in healthcare centres located in deprived neighbourhoods: A randomized controlled trial. European Journal of Cardiovascular Prevention & Rehabilitation, 15(4), 488–493. doi:10.1097/HJR.0b013e3282fceac2