We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and molecular characteristics between the 2 community hospitals. Copyright

doi.org/10.1128/AAC.00074-11, hdl.handle.net/1765/33378
Antimicrobial Agents and Chemotherapy
Erasmus MC: University Medical Center Rotterdam

van der Bij, A., Peirano, G., Goessens, W., van der Vorm, E., van Westreenen, M., & Pitout, J. D. D. (2011). Clinical and molecular characteristics of extended-spectrum-β- lactamase-producing Escherichia coli causing bacteremia in the Rotterdam Area, Netherlands. Antimicrobial Agents and Chemotherapy, 55(7), 3576–3578. doi:10.1128/AAC.00074-11