Purpose: To make a patient- and treatment-specific computed tomography (CT) scan and to create a three-dimensional (3D) patient model for superficial hyperthermia treatment planning (SHTP). Patients, Materials, and Methods: Patients with recurrent breast adenocarcinoma in previously irradiated areas referred for radiotherapy (RT) and hyperthermia (HT) treatment and giving informed consent were included. After insertion of the thermometry catheters in the treatment area, a CT scan in the treatment position was made. Results: A total of 26 patients have been, thus far, included in the study. During the study period, five types of adjustments were made to the procedure: (1) marking the RT field with radioopaque markers, (2) making the CT scan after the first HT treatment instead of before, (3) using an air- and foam-filled (dummy) water bolus, (4) a change to radiolucent catheters for which radioopaque markers were needed, and (5) marking the visible/palpable extent of the tumor with radioopaque markers, if necessary. With these adjustments, all necessary information is visible on the CT scan. Each CT slice was automatically segmented into muscle, fat, bone, and air. RT field, catheters, applicators, and tumor lesions, if indicated, were outlined manually using the segmentation program iSeg. Next the model was imported into SEMCAD X, a 3D electromagnetic field simulator. Conclusion: Using the final procedure to obtain a patient- and treatment-specific CT scan, it is possible to create a 3D model for SHTP.

CT scan, Recurrent breast cancer, Segmentation, Superficial hyperthermia
dx.doi.org/10.1007/s00066-011-2272-0, hdl.handle.net/1765/33585
Strahlentherapie und Onkologie
Erasmus MC: University Medical Center Rotterdam

Linthorst, M.F.G, Drizdal, T, Joosten, H, van Rhoon, G.C, & van der Zee, J. (2011). Procedure for creating a three-dimensional (3D) model for superficial hyperthermia treatment planning. Strahlentherapie und Onkologie, 187(12), 835–841. doi:10.1007/s00066-011-2272-0