The relation between 25-hydroxyvitamin D with peak bone mineral density and body composition in healthy young adults
Objective: The associations between peak bone mineral density (BMD) and body composition with 25 hydroxyvitamin D (25OHD) levels in healthy young adults were evaluated. Methods: The number of participants was 464; 347 women and 117 men. The mean age was 24.3 years (range 17-31 years). BMD of the lumbar spine, total body and femoral neck (FN) and body composition were measured by dual energy X-ray absorptiometry. Volumetric BMD, bone mineral apparent density (BMAD), of the lumbar spine and FN was calculated. Results: In females, 25OHD level was positively associated with FN BMD and BMAD (both p<0.01) and negatively with percentage body fat (p<0.001). In males, 25OHD levels had a positive association with total body BMD and lean body mass (p=0.03 and p=0.01). Conclusions: 25OHD level is a determinant of peak BMD in both sexes. Vitamin D status was associated with body fat in females and with lean body mass in males.
|Keywords||bone mineral density, fat mass, insulin-like growth factor-1, lean body mass, vitamin D|
|Persistent URL||dx.doi.org/10.1515/JPEM.2011.052, hdl.handle.net/1765/33860|
|Journal||Journal of Pediatric Endocrinology & Metabolism|
Boot, A.M, Krenning, E.P, & de Muinck Keizer-Schrama, S.M.P.F. (2011). The relation between 25-hydroxyvitamin D with peak bone mineral density and body composition in healthy young adults. Journal of Pediatric Endocrinology & Metabolism, 24(5-6), 355–360. doi:10.1515/JPEM.2011.052