2011-08-01
CD73 (5′-nucleotidase) expression has no prognostic value in children with acute lymphoblastic leukemia
Publication
Publication
Leukemia , Volume 25 - Issue 8 p. 1374- 1376
Ecto-50-nucleotidase, also known as CD73, is a glycosyl phosphatidylinositol-linked enzyme on the cell surface of a variety of cell types,1,2 which catalyzes the dephosphorylation of AMP and other nucleoside monophosphates. CD73, originally defined as a lymphocyte differentiation antigen, is thought to function as an adhesion molecule necessary for lymphocyte binding to endothelium3 and a co-signaling molecule on T lymphocytes when ligated by antibodies. [...]
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| doi.org/10.1038/leu.2011.174, hdl.handle.net/1765/33953 | |
| Leukemia | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Wieten, E., van der Linden-Schrever, B. E. M., Sonneveld, E., Veerman, A., & Pieters, R. (2011). CD73 (5′-nucleotidase) expression has no prognostic value in children with acute lymphoblastic leukemia. Leukemia, 25(8), 1374–1376. doi:10.1038/leu.2011.174 |
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