Paradoxical Effects of Interatrial Conduction Delay. We present a unique case where early proarrhythmic and late antiarrhythmic characteristics of interatrial conduction delay were observed during the long-term progression of HCM. Occurrence of AT constantly increased as the interatrial conduction delay became more prominent, while the P-wave width in sinus rhythm and the AT cycle length both showed an instantaneous increase in parallel. As the interatrial delay reached a critical point, the right and left atrial P-wave became virtually separated, as demonstrated by the findings of ECGs and echocardiography. This phenomenon resulted in the complete cessation of tachycardias. (J Cardiovasc Electrophysiol, Vol. 22, pp. 587-589 May 2011)

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Journal of Cardiovascular Electrophysiology
Erasmus MC: University Medical Center Rotterdam

Bauernfeind, T., Caliskan, K., Vletter, W. B., ten Cate, F., Dabiri, L., de Groot, N., … Szili-Török, T. (2011). Paradoxical effects of interatrial conduction delay in a hypertrophic cardiomyopathy patient in the long-term: Time is a great healer. Journal of Cardiovascular Electrophysiology, 22(5), 587–589. doi:10.1111/j.1540-8167.2010.01893.x