We investigated the role of donor cytomegalovirus (CMV) serostatus on reactivation of CMV infection in CMV-infected transplant recipients. Reactivation of CMV infection occurred more frequently in patients receiving a CMV-positive graft but was less severe than in patients receiving a CMV-negative graft. These data suggest roles for both virus as well as CMV-specific immunity present in the graft.

doi.org/10.1093/cid/cir002, hdl.handle.net/1765/34225
Clinical Infectious Diseases
Erasmus MC: University Medical Center Rotterdam

Pietersma, F., van Dorp, S., Minnema, M., Kuball, J., Meijer, E., Schuurman, R., & van Baarle, D. (2011). Influence of donor cytomegalovirus (CMV) status on severity of viral reactivation after allogeneic stem cell transplantation in CMV-seropositive recipients. Clinical Infectious Diseases, 52(7). doi:10.1093/cid/cir002