Background. Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis. Methods. and Results. We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy. Conclusions. Our patient now has a recurrence-free survival of >20 months, longer than the mean survival described in the literature.

carcinoma, cell, radiochemotherapy, squamous, thyroid
dx.doi.org/10.1002/hed.21484, hdl.handle.net/1765/34858
Head and Neck Oncology
Erasmus MC: University Medical Center Rotterdam

de Vos, F.Y.F.L, Sewnaik, A, de Wilt, J.H.W, Smid, E.J, den Bakker, M.A, & van Meerten, E. (2012). Combined therapy for thyroid squamous cell carcinoma. Head and Neck Oncology, 34(1), 131–134. doi:10.1002/hed.21484