Background. Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis. Methods. and Results. We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy. Conclusions. Our patient now has a recurrence-free survival of >20 months, longer than the mean survival described in the literature.

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Head and Neck Oncology
Erasmus MC: University Medical Center Rotterdam

de Vos, F. Y. F. L., Sewnaik, A., de Wilt, J., Smid, E., den Bakker, M., & van Meerten, E. (2012). Combined therapy for thyroid squamous cell carcinoma. Head and Neck Oncology, 34(1), 131–134. doi:10.1002/hed.21484