Intensity modulated radiation therapy planning for patients with a metal hip prosthesis based on class solutions
Practical Radiation Oncology , Volume 2 - Issue 1 p. 35- 40
Purpose: With the aging of the population, an increasing number of patients with metallic hip implants are referred for radiotherapy treatment. Class solutions for intensity modulated radiation therapy (IMRT) treatment planning are generally not applicable for these patients due to the required avoidance of dose delivery through prostheses. In this work a new approach for IMRT planning is presented, allowing the use of a default beam setup. Methods and Materials: For IMRT planning, Monaco (Elekta; CMS Software, Maryland Heights, MO) was used. In addition to the target and organs at risk, so-called prosthesis avoidance volumes (PAVs) were delineated in the beam's eye view projection for beams in which the prosthesis was partially in front of the target. By putting strict constraints on these virtual organs at risk, entrance dose delivery through a prosthesis is avoided while exit dose delivery is allowed. In this way, uncertainties in the dose delivery to the target and organs at risk, as derived by the treatment planning system, are largely minimized. To show the advantages of this IMRT-PAV technique, for 2 prostate cancer patients, 1 with bilateral and the other with unilateral metallic hip prostheses, obtained IMRT plans were compared with conventional IMRT plans using a prosthesis-avoiding beam setup. Results: For both IMRT techniques a similar planning target volume coverage was achieved, but with the IMRT-PAV technique the mean doses to the bladder and the rectum were reduced by up to 25%. While the IMRT-PAV technique required more time for delineation, the time for treatment planning reduced because the default beam setup could be applied. The number of segments needed for dose delivery was comparable for both techniques. Conclusions: With the new IMRT-PAV technique IMRT class solutions can safely be applied for cancer patients with metallic hip prostheses, generally yielding a reduced dose delivery to organs at risk or improved target coverage.
|Practical Radiation Oncology|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
van der Est, H, Prins, B.P, Heijmen, B.J.M, & Dirkx, M.L.P. (2012). Intensity modulated radiation therapy planning for patients with a metal hip prosthesis based on class solutions. Practical Radiation Oncology, 2(1), 35–40. doi:10.1016/j.prro.2011.04.006